ABSTRACT
ABSTRACTA 28-year-old man presented with bilateral vision loss. His best-corrected visual acuity (BCVA) was 0.3 in the right eye (OD) and 0.6 in the left eye (OS). Fundoscopy and fluorescein angiography showed angioid streaks encircling the optic discs of both eyes (OU). Spectral Domain Optical Coherence Tomography (SD-OCT) showed bilateral macular serous detachment. Systemic and ocular screening tests showed no specific cause for the angioid streaks. The patient had previously received pegaptanib sodium injection on three occasions, photodynamic therapy in OS, and no treatment in OD. Upon intravitreal injection of ranibizumab (twice in OU), subretinal fluid was nearly eliminated in OU. BCVA increased to 0.6 in OD and 0.9 in OS, and remained improved until 6 months after treatment.
RESUMOUm homem de 28 anos apresentou-se com perda de visão bilateral. A melhor acuidade visual corrigida (BCVA) era 0,3 no olho direito (OD) e 0,6 no olho esquerdo (OS). A fundoscopia e a angiofluoresceinografia demonstraram estrias angióides ao redor dos discos ópticos em ambos os olhos (OU). A tomografia de coerência óptica de domínio espectral (SD-OCT) demonstrou descolamento seroso macular bilateral. Testes de triagem sistêmicas e oculares não mostraram causa específica para estrias angióides. O paciente tinha um historia de três tratamentos com injeção de pegaptanibe sódico e terapia fotodinâmica em OS e nenhum tratamento em OD. Após a injeção intravítrea de ranibizumabe (duas vezes em OU), fluido sub-retiniano quase desapareceu em OU. BCVA melhorou para 0,6 em OD e 0,9 em OS e não se alterou até o sexto mês de tratamento.
Subject(s)
Adult , Humans , Male , Angiogenesis Inhibitors/therapeutic use , Angioid Streaks/drug therapy , Antibodies, Monoclonal/administration & dosage , Choroidal Neovascularization/drug therapy , Ranibizumab/therapeutic use , Antibodies, Monoclonal, Humanized , Angioid Streaks/complications , Bevacizumab/therapeutic use , Choroidal Neovascularization/etiology , Fluorescein Angiography , Intravitreal Injections , Tomography, Optical Coherence , Visual AcuityABSTRACT
ABSTRACT Purpose: The aim of this study was to explore the effect of age on the success of transcanalicular diode laser-assisted dacryocystorhinostomy (TCDCR). Methods: Seventy patients (70 eyes) who underwent transcanalicular diode laser-assisted dacryocystorhinostomy for the treatment of nasolacrimal duct obstruction as a primary surgery were included in this retrospective, nonrandomized study. The patients were divided into two groups according to age. Mean ages were 21.3 ± 3.3 in group 1 and 60.3 ± 7.3 in group 2. The records of the 3-, 6-, and 12-month follow-up examinations were evaluated, and the anatomical and functional outcomes were noted. Functional success was defined as the absence of epiphora as indicated by the patient. Anatomical success was determined as patency of the neo-ostium with irrigation. Results: At the 3-month follow-up, 67% cases in group 1 showed anatomical success and 52% showed functional success; in group 2, the rates were 100% and 92%, respectively. Functional and anatomical success rates were the same for both the 6- and 12-month visits; 46% in group 1 and 76% in group 2. The results in group 2 were significantly better at all three follow-up visits (p<0.05). Conclusions: This study clearly showed that the older patients experienced better transcanalicular diode laser-assisted dacryocystorhinostomy results than the younger patients. The diminished inflammatory response in the older population may be a possible contributing factor to these results. .
RESUMO Objetivo: O objetivo deste estudo foi explorar o efeito da idade sobre o sucesso de dacriocistorrinostomia transcanalicular auxiliada por laser de diodo (TCDCR). Método: Setenta olhos de setenta pacientes submetidos dacriocistorrinostomia transcanalicular auxiliada por laser de diodo para o tratamento da obstrução nasolacrimal como cirurgia primária foram incluídos neste estudo retrospectivo, não randomizado. Os pacientes foram divididos em dois grupos segundo a idade. As idades médias foram 21,3 ± 3,3 no grupo 1 e 60,3 ± 7,3 no grupo 2. Os registros do acompanhamento pós-operatório aos três, seis e 12 meses, foram avaliados, observando resultados anatômicos e funcionais. Sucesso funcional foi definido como a ausência de lacrimejamento, conforme informado pelo paciente. Sucesso anatômico foi determinado como a permeabilidade do novo óstio à irrigação. Resultados: Nos três meses de acompanhamento, 67% dos casos no grupo 1 apresentou sucesso anatômico, e 52% mostraram sucesso funcional. No grupo 2, as taxas foram de 100% e 92%, respectivamente. Taxas de sucesso funcionais e anatômicas foram as mesmas para ambos os seis e 12 meses de visitas: 46% no grupo 1 e 76% no grupo 2. Os resultados do grupo 2 foram significativamente melhores em todas as três visitas pós-operatorias (p<0,05). Conclusões: Este estudo mostra claramente que os pacientes mais idosos apresentam melhores resultados à dacriocistorrinostomia transcanalicular auxiliada por laser de diodo comparados aos mais jovens. A resposta inflamatória diminuída na população mais velha é um possível fator que contribuiu para estes resultados. .
Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Young Adult , Age Factors , Dacryocystorhinostomy/methods , Lacrimal Duct Obstruction/therapy , Lasers, Semiconductor/therapeutic use , Nasolacrimal Duct/surgery , Cicatrix/complications , Follow-Up Studies , Operative Time , Postoperative Complications , Postoperative Period , Protective Factors , Retrospective Studies , Silicones/therapeutic use , Treatment OutcomeABSTRACT
A 20‑year‑old man applied with vision loss in the left eye. Right eye examination was unremarkable. Best‑corrected visual acuity (BCVA) in the left eye was 20/200. Fundus examination revealed a few yellow spots within a round‑shaped macular lesion. Autofluorescence imaging showed hyperautofluorescence in the lesion. Central amplitudes in multifocal electroretinogram (mfERG) were depressed. The patient reported a rhinopharyngitis 7–10 days before the visual loss. The patient was diagnosed as acute retinal pigment epithelitis. BCVA improved gradually up to 20/20 in 4 weeks. mfERG amplitudes returned to normal. A slight pigmentary distortion was the only residual fundus finding.
ABSTRACT
Purpose: To determine the effect of a capsular tension ring (CTR) implantation in preventing posterior capsular opacification (PCO) after cataract surgery in patients with high myopia. Materials and Methods: In this prospective single‑surgeon standardized‑surgical‑procedure fellow‑eye comparison trial, 34 patients with high myopia had phacoemulsification surgery. Although one eye received an acrylic intraocular lens (IOL) and CTR, other eye received only an IOL as control. PCO, within the capsulorhexis overlap, was documented by standardized digital retroillumination images at least 2 years post‑operatively, and the percentage area of PCO was scored (scale 0%‑100%) using the POCOman software system. The PCO score and the incidence of neodymium‑doped yttrium aluminum garnet (Nd: YAG) capsulotomy of groups, and correlations between PCO score and presence of CTR, age, phaco time, refraction, and axial length (AL) were determined. Results: The mean time interval from surgery to PCO measurement was 43.4 ± 11.2 months for the eyes with a CTR and 43.1 ± 11.6 months for the controls (P = 0.91). The PCO score of the eyes with a CTR was significantly lower than in the controls (5.9 ± 4.3 vs. 22.3 ± 12.2, respectively; P < 0.001). There were statistically insignificant correlations between PCO score and pre‑operative refraction (r = 0.02; P = 0.90), AL (r = 0.03; P = 0.80), phaco time (r = 0.11; P = 0.53), and patient’s age (r = 0.23; P = 0.55). No patient with a CTR had a Nd: YAG laser capsulotomy, but it was six in controls (P = 0.025). Conclusions: CTR implantation seems to be effective in reducing the PCO and Nd: YAG laser capsulotomy rates in high myopic eyes.
ABSTRACT
Background: Optic pathway involvement in multiple sclerosis is frequently the initial sign in the disease process. In most clinical applications, pattern visual evoked potential (PVEP) is used in the assessment of optic pathway involvement. Objective: To question the value of PVEP against color vision assessment in the diagnosis of subclinical optic pathway involvement. Materials and Methods: This prospective, cross-sectional study included 20 multiple sclerosis patients without a history of optic neuritis, and 20 healthy control subjects. Farnsworth-Munsell (FM) 100-Hue testing and PVEPs to 60-min arc and 15-min arc checks by using Roland-Consult RetiScan® system were performed. P100 amplitude, P100 latency in PVEP and total error scores (TES) in FM 100-Hue test were assessed. Results: Expanded Disability Status Scale score and the time from diagnosis were 2.21 ± 2.53 (ranging from 0 to 7) and 4.1 ± 4.4 years. MS group showed significantly delayed P100 latency for both checks (P < 0.001). Similarly, MS patients had significantly increased total error scores (TES) in FM-100 Hue (P < 0.001). The correlations between TESs and PVEP amplitudes / latencies were insignificant for both checks (P > 0.05 for all). 14 MS patients (70%) had an increased TESs in FM-100 Hue, 11 (55%) MS patients had delayed P100 latency and 9 (45%) had reduced P100 amplitude. The areas under the ROC curves were 0.944 for FM-100 Hue test, 0.753 for P100 latency, and 0.173 for P100 amplitude. Conclusions: Color vision testing seems to be more sensitive than PVEP in detecting subclinical visual pathway involvement in MS.
ABSTRACT
Partial optic nerve avulsion (ONA) secondary to finger gouging is an uncommon but devastating injury. A 21-year-old man who had an acute vision loss after accidentally getting poked by himself in his right eye when he fell down during jogging is reported. The patient was diagnosed with partial ONA. Magnetic resonance imaging revealed intact optic nerve. Optical coherence tomography (OCT) revealed deep cavity at the inferior-temporal half of the optic disc. Retinal nerve fiber layer thickness was also thin at the inferior quadrant with circumpapillary OCT scan. Visual field test and electrophysiological tests showed functional abnormality compatible with optic nerve lesion. Diagnostic tools for anatomical and functional evaluation may reveal the course of this injury.